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A 6-year old boy with 2 years history of asthma has well controlled under inhaled steroid for 3month. A moment ago,he felt breathlessness and begun wheezing after activity, which medication does he need most urgently?
A: Inhaled corticosteroid
B: Systemic Corticosteroids
C: Leukotriene modifiers
D: Inhaled Rapid-Acting Beta2-agonists
E: Oral Rapid-Acting Beta2-agonists
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